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Semin Plast Surg 2003; 17(1): 099-106
DOI: 10.1055/s-2003-39860
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Soft Tissue Restoration Using Tissue Engineering

Parul Patel1,2 , Geoffrey L. Robb, Charles W. Patrick, Jr.2,3
  • 1Department of Chemical Engineering, Rice University, Houston, TX
  • 2Laboratory of Reparative Biology and Bioengineering, Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • 3The University of Texas Center for Biomedical Engineering, Houston, TX
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Publication History

Publication Date:
16 June 2003 (online)

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ABSTRACT

The correction of soft tissue defects caused by trauma, tumor resection, congenital abnormalities, and aging presents a challenge in plastic surgery. Soft tissue defects run the gamut in terms of volume, from restoring the fullness of the face by removing wrinkles to restoring the breast mound after mastectomy. The limitations of current techniques have served as drivers for the development of adipose tissue as an application area for tissue engineering. Tissue engineering is a growing field that combines bioengineering, the clinical sciences, and the life sciences to repair or regrow tissues. This article discusses the inadequacies of current methods of correcting soft tissue defects and the innovative adipose tissue engineering strategies under pursuit to abrogate these limitations and improve patient outcomes and quality of life.

KEYWORDS

Adipose tissue - biomedical engineering - breast reconstruction - soft tissue augmentation - tissue engineering - tissue scaffolds

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