Thorac Cardiovasc Surg 2003; 51(2): 99-101
DOI: 10.1055/s-2003-38982
Case Report
© Georg Thieme Verlag Stuttgart · New York

Ex situ Resection of Primary Cardiac Tumors

A.  Hoffmeier1 , H.  H.  Scheld1 , T.  D. T.  Tjan1 , M.  Schneider1 , S.  Kerber2 , C.  Schmidt3 , C.  Schmid1
  • 1Department of Thoracic and Cardiovascular Surgery, University Hospital, Westfälische Wilhelms-University, Münster, Germany
  • 2Department of Cardiology, Cardiovascular Center, Bad Neustadt/Saale, Germany
  • 3Department of Anesthesiology and Operative Intensive Care, University Hospital, Westfälische Wilhelms-University, Münster, Germany
Further Information

Publication History

Received: December 15, 2002

Publication Date:
05 May 2003 (online)

Abstract

The prognosis of malignant heart tumors is pessimistic; 50 % of patients die within 6 months. No optimal therapy has been established, and standardized therapeutic concepts have not been developed due to the low incidence of this disease. In most cases, chemotherapy and radiotherapy have not shown any survival benefit compared to surgical treatment. Obviously, radical resection of the tumor is the most important determinant for long-term survival. Here, we report on two patients in whom radical resection of heart tumors could be accomplished only after explantation of the heart.

References

  • 1 Crafoord C L. Discussion on mitral stenosis and insufficiency. In: Lane CR (ed) Proceedings of the International Symposium on Cardiovascular Surgery. Henry Ford Hospital 1955: 202
  • 2 Murphy M C, Sweeney M S, Putnam J B. et al . Surgical treatment of cardiac tumors: a 25-year experience.  Ann Thorac Surg. 1990;  49 612-617 ,  Discussion 17 - 18
  • 3 Centofanti P, Di Rosa E, Deorsola L. et al . Primary cardiac tumors: early and late results of surgical treatment in 91 patients.  Ann Thorac Surg. 1999;  68 1236-1241
  • 4 Kamiya H, Yasuda T, Nagamine H. et al . Surgical treatment of primary cardiac tumors: 28 years' experience in Kanazawa University Hospital.  Jpn Circ J. 2001;  65 315-319
  • 5 Cooley D A, Readon M J, Frazier O H, Angeline P. Human cardiac explantation and autotransplantation: Application in a patient with a large cardiac pheochromocytoma.  Texas Heart Institute Journal. 1985;  12 171-176
  • 6 Kosak M, Gabrijelcic T, Brecelj A. et al . [The world's first successful autotransplantation of the heart for recurrent tumor].  Acta Chir Jugosl. 1987;  34 131-139
  • 7 Scheld H H, Nestle H W, Kling D. et al . Resection of a heart tumor using autotransplantation.  Thorac Cardiovasc Surg. 1988;  36 40-43
  • 8 Kitamura N, Yamaguchi A, Miki T. et al . [Autotransplantation as optimal technique for recurrent malignant myxoma of left ventricle].  Nippon Kyobu Geka Gakkai Zasshi. 1993;  41 445-451
  • 9 Reardon M J, DeFelice C A, Sheinbaum R, Baldwin J C. Cardiac autotransplant for surgical treatment of a malignant neoplasm.  Ann Thorac Surg. 1999;  67 1793-1795
  • 10 Wagner S, Hutchisson B, Baird M G. Cardiac explantation and autotransplantation.  Aorn J. 1999;  70 99-100 ,  02, 04-7; quiz 08
  • 11 Akiyama K, Purba R, Scheld H H, Hehrlein F W. Successful surgical treatment for left atrial myoxma by cardiac autotransplantation.  Rinsho Kyobu Geka. 1988;  8 398-401
  • 12 Butany J, Yu W. Cardiac angioscarcoma: two cases and a review of the literature.  Can J Cardiol. 2000;  16 197-205
  • 13 Llombart-Cussac A, Pivot X, Contesso G. et al . Adjuvant chemotherapy for primary cardiac sarcomas: the IGR experience.  Br J Cancer. 1998;  78 1624-1628
  • 14 Kakizaki S, Takagi H, Hosaka Y. Cardiac angiosarcoma responding to multidisciplinary treatment.  Int J Cardiol. 1997;  62 273-275
  • 15 Nakamichi T, Fukuda T, Suzuki T, Kaneko T, Morikawa Y. Primary cardiac angiosarcoma: 53 months' survival after multidisciplinary therapy.  Ann Thorac Surg. 1997;  63 1160-1161
  • 16 Ceresoli G L, Ferreri A J, Buci E. et al . Primary cardiac lymphoma in immunocompetent patients: diagnostic and therapeutic management.  Cancer. 1997;  80 1497-1506
  • 17 A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project. Blood 1997 89: 3909-3918
  • 18 Harris N L, Jaffe E S, Stein H. et al . A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group.  Blood. 1994;  84 1361-1392
  • 19 Vander Salm T J. Unusual primary tumors of the heart.  Semin Thorac Cardiovasc Surg. 2000;  12 89-100
  • 20 Piper S N, Werner U, Maleck W H. et al . Recurrent atrial sarcoma presenting as an atrial myxoma. Long-term survival due to surgical intervention and chemotherapy.  J Cardiovasc Surg (Torino). 2000;  41 961-964
  • 21 Livi U, Rizzoli G. Autotransplantation procedure for giant left atrium repair.  Heart Surg Forum. 1998;  1 71-75
  • 22 Lessana A, Scorsin M, Scheuble C, Raffoul R, Rescigno G. Effective reduction of a giant left atrium by partial autotransplantation.  Ann Thorac Surg. 1999;  67 1164-1165
  • 23 Wei J, Wu C, Hong G. et al . Autotransplantation of heart for repair of left ventricular rupture after mitral valve replacement.  Transplant Proc. 2001;  33 3553-3554
  • 24 Pfeiffer D, Fiehring H, Warnke H, Pech H J, Jenssen S. Treatment of tachyarrhythmias in a patient with the long QT syndrome by autotransplantation of the heart and sinus node-triggered atrial pacing.  J Thorac Cardiovasc Surg. 1992;  104 491-494
  • 25 Bertrand M E, Lablanche J M, Tilmant P Y. et al . Complete denervation of the heart (autotransplantation) for treatment of severe, refractory coronary spasm.  Am J Cardiol. 1981;  47 1375-1378
  • 26 Bertrand M E, Lablanche J M, Tilmant P Y. et al . [Treatment of a severe coronary artery spasm, refractory to complete denervation of the heart (autotransplantation)].  Arch Mal Coeur Vaiss. 1982;  75 717-723
  • 27 Gowdamarajan A, Michler R E. Therapy for primary cardiac tumors: is there a role for heart transplantation?.  Curr Opin Cardiol. 2000;  15 121-125

Correspondence

Andreas Hoffmeier, M.D. 

Department of Thoracic and Cardiovascular Surgery, University Hospital

Albert-Schweitzer-Straße 33

48149 Münster

Germany

Phone: + 49-251-8347401

Fax: + 49-251-8348616

Email: andreas.hoffmeier@thgms.uni-muenster.de