Medikamentöse Therapie bei Aszites und hepatorenalem Syndrom

Glossar: ADH - Antidiuretisches Hormon; HRS - hepatorenales Syndrom; RAAS - Renin-Angiotensin-Aldosteronsystem; SNS - sympathisches Nervensystem; TIPS - transjugulärer intrahepatischer portosystemischer Shunt.

Literatur

• 1 Angeli P, Volpin R, Gerunda G, Craighero R, Roner P, Merenda R, Amodio P, Sticca A, Caregaro L, Maffei-Faccioli A, Gatta A. Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide.  Hepatology. 1999;  29 1690-1697
• 2 Arroyo V, Gines P, Gerbes A L, Dudley F, Gentilini P, Laffi G, Reynolds T B, Ring-Larsen H, Schölmerich J. Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis.  Hepatology. 1996;  23 164-176
• 3 Brensing K A, Textor J, Perz J, Schiedermaier P, Raab P, Strunk H, Klehr H U, Kramer H J, Spengler U, Schild H, Sauerbruch T. Long term outcome after transjugular intrahepatic portosystemic stent-shunt in non-transplant cirrhotics with hepatorenal syndrome: a phase II study.  Gut. 2000;  47 288-295
• 4 Christidis C, Mal F, Ramos J. et al . Worsening of hepatic dysfunction as a consequence of repeated hydroxyethylstarch infusions.  J Hepatol. 2001;  35 726-732
• 5 Gerbes A L, Gülberg V, Gines P, Decaux G, Gross P, Gandjini H, Djian J. and the VPA study group . Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist - a randomized controlled multicenter trial.  Gastroenterology. 2003;  in press
• 6 Ginès A, Escorsell A, Ginès P. et al . Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites.  Gastroenterology. 1993;  105 229-236
• 7 Gines A, Fernandez-Esparrach G, Monescillo A. et al . Randomized trial comparing albumin, dextran 70 and polygeline in cirrhotic patients with ascites treated by paracentesis.  Gastroenterology. 1996;  111 1002-1010
• 8 Ginès P, Arroyo V. Hepatorenal syndrome.  J Am Soc Nephrol. 1999;  10 1833-1839
• 9 Gines P, Tito L, Arroyo V. et al . Randomized comparative study of therapeutic paracentesis with and without intravenous albumin in cirrhosis.  Gastroenterology. 1988;  94 1493-1502
• 10 Gonwa T A, Klintmalm G B, Levy M, Jennings L S, Goldstein R M, Husberg B S. Impact of pretransplant renal function on survival after liver transplantation.  Transplantation. 1995;  59 361-365
• 11 Gülberg V, Bilzer M, Gerbes A L. Long-term therapy and retreatment of hepatorenal syndrome type 1 with ornipressin and dopamine.  Hepatology. 1999;  30 870-875
• 12 Gülberg V, Gerbes A L. Diagnostik und Therapie des Aszites bei Leberzirrhose.  Internist (Berl.). 1998;  39 254-262
• 13 Gülberg V, Gerbes A L. TIPS or Vasoconstrictors for the Treatment of Hepatorenal Syndrome Type 1 - Effect on Survival?.  Z Gastroenterol. 2002;  40 823-826
• 14 Jimenez W, Serradeil-Le Gal C, Ros J, Carmen C, Rivera F, Arroyo V. Aquaretic efficacy of the V2-vasopressin (AVP) receptor antagonist SR 121 463 in cirrhotic rats with ascites.  Hepatology. 1999;  30 232A
• 15 Lenz K, Hörtnagl H, Druml W, Reither H, Schmid R, Schneeweiss B, Laggner A, Grimm G, Gerbes A L. Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis. Effects on renal hemodynamics and atrial natriuretic factor.  Gastroenterology. 1991;  101 1060-1067
• 16 Møller S, Henriksen J H. The systemic circulation in cirrhosis. London: Blackwell In Arroyo V, Gines P, Rodes J, Schrier RW (eds.). Ascites and renal dysfunction in liver disease 1999: 307-329
• 17 Moreau R, Durand F, Poynard T. et al . Terlipressin in patients with cirrhosis and type 1 hepatorenal syndrome: a retrospective multicenter study.  Gastroenterology. 2002;  122 923-930
• 18 Schrier R W, Arroyo V, Bernardi M, Epstein M, Henriksen J H, Rodes J. Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis.  Hepatology. 1988;  8 1151-1157
• 19 Sort P, Navasa M, Arroyo V. et al . Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis.  N Engl J Med. 1999;  341 403-409
• 20 Tito L, Gines P, Arroyo V. et al . Total paracentesis with intravenous albumin management of patients with cirrhosis and ascites.  Gastroenterology. 1990;  98 146-151
• 21 Uriz J, Ginès P, Cárdenas A, Sort P, Jiménez W, Salmerón J M, Bataller R, Mas A, Navasa M, Arroyo V, Rodés J. Terlipressin plus albumin infusion: an effective and safe therapy of hepatorenal syndrome.  J Hepatol. 2000;  33 43-48