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Semin intervent Radiol 2002; 19(3): 235-244
DOI: 10.1055/s-2002-35328
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Kyphoplasty for the Treatment of Vertebral Compression Fractures

Kamran Ahrar1 , Donald F. Schomer2 , Michael J. Wallace1
  • 1Department of Vascular and Interventional Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
  • 2Department of Neuroradiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
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Publication History

Publication Date:
07 November 2002 (online)

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ABSTRACT

Vertebral compression fractures are the most common fragility fractures, and they have significant medical and economical consequences. Conventional medical therapy for these fractures is aimed at treatment of symptoms with bed rest, analgesic medications, and bracing. Surgery is reserved for those patients with neurological deficits or compression of neural elements. Percutaneous vertebroplasty (PVP) has emerged as a minimally invasive treatment option to strengthen the fractured vertebra and to relieve associated pain. Percutaneous kyphoplasty (PKP) is a novel technique designed to relieve pain, strengthen the fractured vertebra, and restore the height of the compressed vertebra, thus minimizing the spinal deformity and its adverse sequelae. This article provides a brief introduction to this new technique and its current status in clinical practice.

KEYWORDS

Vertebral compression fracture - vertebroplasty - kyphoplasty

REFERENCES

  • 1 Cooper C, Atkinson E J, O'Fallon W M, Melton III J L. Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota, 1985-1989.  J Bone Miner Res . 1992;  7 221-227
    CrossrefPubMedGoogle Scholar
  • 2 Heaney R P. The natural history of vertebral osteoporosis. Is low bone mass an epiphenomenon?.  Bone . 1992;  13 S23-S26
    CrossrefPubMedGoogle Scholar
  • 3 Cohen L D. Fractures of the osteoporotic spine.  Orthop Clin North Am . 1990;  21 143-150
    PubMedGoogle Scholar
  • 4 Rapado A. General management of vertebral fractures.  Bone . 1996;  18 191S-196S
    CrossrefPubMedGoogle Scholar
  • 5 Mathis J M, Barr J D, Belkoff S M. Percutaneous vertebroplasty: a developing standard of care for vertebral compression fractures.  Am J Neuroradiol . 2001;  22 373-381
    PubMedGoogle Scholar
  • 6 Jensen M E, Evans A J, Mathis J M. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects.  Am J Neuroradiol . 1997;  18 1897-1904
    PubMedGoogle Scholar
  • 7 Barr J D, Barr M S, Lemley T J, McCann R M. Percutaneous vertebroplasty for pain relief and spinal stabilization.  Spine . 2000;  25 923-928
    CrossrefPubMedGoogle Scholar
  • 8 Lyles K W, Gold D T, Shipp K M. Association of osteoporotic vertebral compression fractures with impaired functional status.  Am J Med . 1993;  94 595-601
    CrossrefPubMedGoogle Scholar
  • 9 Silverman S L. The clinical consequences of vertebral compression fracture.  Bone . 1992;  13 S27-S31
    CrossrefPubMedGoogle Scholar
  • 10 Schlaich C, Minne H W, Bruckner T. Reduced pulmonary function in patients with spinal osteoporotic fractures.  Osteoporos Int . 1998;  8 261-267
    CrossrefPubMedGoogle Scholar
  • 11 Leech J A, Dulberg C, Kellie S, Pattee L, Gay J. Relationship of lung function to severity of osteoporosis in women.  Am Rev Respir Dis . 1990;  141 68-71
    CrossrefPubMedGoogle Scholar
  • 12 Kado D M, Browner W S, Palermo L. Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group.  Arch Intern Med . 1999;  159 1215-1220
    Google Scholar
  • 13 Wong W, Reiley M A, Garfin S. Vertebroplasty/kyphoplasty.  Journal of Women's Imaging . 2000;  2 117-124
    PubMedGoogle Scholar
  • 14 Belkoff S M, Mathis J M, Fenton D C. An ex vivo biomechanical evaluation of an inflatable bone tamp used in the treatment of compression fracture.  Spine . 2001;  26 151-156
    CrossrefPubMedGoogle Scholar
  • 15 Jensen M E, Dion J E. Percutaneous vertebroplasty in the treatment of osteoporotic compression fractures.  Neuroimaging Clin North Am . 2000;  10 547-568
    PubMedGoogle Scholar
  • 16 Cotten A, Dewatre F, Cortet B. Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up.  Radiology . 1996;  200 525-530
    CrossrefPubMedGoogle Scholar
  • 17 Mathis J M, Petri M, Naff N. Percutaneous vertebroplasty treatment of steroid-induced osteoporotic compression fractures.  Arthritis Rheum . 1998;  41 171-175
    CrossrefPubMedGoogle Scholar
  • 18 Belkoff S M, Dremond H, Mathis J M, Jasper L. Vertebroplasty: the biomechanical effect of cement volume (Abst).  Trans Orthop Res Soc . 2000;  25 356
    PubMedGoogle Scholar
  • 19 Tohmeh A G, Mathis J M, Fenton D C, Levine A M, Belkoff S M. Biomechanical efficacy of unipedicular versus bipedicular vertebroplasty for the management of osteoporotic compression fractures.  Spine . 1999;  24 1772-1776
    CrossrefPubMedGoogle Scholar
  • 20 Lane J M, Girardi F P, Khan S N. Preliminary outcomes of the first 226 consecutive kyphoplasties for the fixation of painful osteoporotic vertebral compression fractures.  J Bone Miner Res . 2000;  15 S198
    PubMedGoogle Scholar
  • 21 Yuan H A, Garfin S R, Lieberman I H, Reiley M A, Yonemura K. Early clinical outcomes with kyphoplasty, the minimally-invasive reduction of painful osteoporotic vertebral body compression fracture. Paper presented at the section on Disorders of the Spine and Peripheral Nerves, 16th Annual Meeting of American Association of Neurological Surgeons and Congress of Neurological Surgeons; February 23-26, 2000; Indian Wells, California
    Google Scholar