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Synthesis 2002(14): 2143-2149
DOI: 10.1055/s-2002-34369
DOI: 10.1055/s-2002-34369
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Polyfunctional Unsaturated Amines by the Addition of Functionalized Organomagnesium Reagents to Unsaturated Imminium Ions
Weitere Informationen
Received
18 July 2002
Publikationsdatum:
26. September 2002 (online)
Publikationsverlauf
Publikationsdatum:
26. September 2002 (online)
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Abstract
The reaction of propargylic and allylic aminals with trifluoromethanesulfonic anhydride at low temperature produces imminium salts, which react in the presence of N-methylpyrrolidinone (NMP) with functionalized arylmagnesium compounds, providing polyfunctional propargylic and allylic amines in satisfactory yields.
Key words
functionalized organomagnesium reagents - imminium salts - propargylic amines - allylic amines - aminals
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