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Synthesis 2002(6): 0784-0788
DOI: 10.1055/s-2002-25775
PAPER
© Georg Thieme Verlag Stuttgart · New York

Iodine-Catalyzed, Efficient and Mild Procedure for Highly Chemoselective Acetalization of Carbonyl Compounds under Neutral Aprotic Conditions

Babak Karimi*, Behzad Golshani
Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), P.O.Box 45195-159, Gava Zang, Zanjan, Iran
Fax: +98(241)4249023; e-Mail: Karimi@iasbs.ac.ir;
Further Information

Publication History

Received 2 January 2002
Publication Date:
26 April 2002 (online)

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Abstract

Various types of carbonyl compounds are efficiently converted to their 1,3-dioxanes by the use of 1,3-bis(trimethylsiloxy)propane (BTSP) and a catalytic amount of iodine (3-7 mol%) under essentially neutral aprotic condition.

Key words

carbonyl compounds - chemoselectivity - protection - 1,3-bis(trimethylsiloxy)propane - iodine

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