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Synthesis 2002(6): 0757-0760
DOI: 10.1055/s-2002-25773
PAPER
© Georg Thieme Verlag Stuttgart · New York

Efficient Synthesis of Substituted Terphenyls by Suzuki Coupling Reaction [1]

Hélène Chaumeil*, Claude Le Drian, Albert Defoin
Laboratoire de Chimie Organique et Bio-organique, U.M.R. 7015, Ecole Nationale Supérieure de Chimie de Mulhouse, 3, rue Alfred Werner, 68093 Mulhouse Cedex, France
Fax: +33(3)89336860; e-Mail: h.chaumeil@uha.fr;
Further Information

Publication History

Received 26 November 2001
Publication Date:
26 April 2002 (online)

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Abstract

The Suzuki cross-coupling reactions of phenyl-1,4-dibor­onic acid bis-pinacol ester with a range of aryl halides are reported. The reaction proceeded smoothly, even with sterically hindered aryl halides, to give symmetrical terphenyls often quantitatively.

Key words

cross-coupling reaction - boronic esters - aryl halides - steric hindrance - terphenyls

1

Chaumeil H., Le Drian C. 31ème séminaire Hors-Ville d’Automne and 21st Regio Symposium in Organic and Bioorganic chemistry, 16-20th September 2001, Champery, Switzerland.

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1

Chaumeil H., Le Drian C. 31ème séminaire Hors-Ville d’Automne and 21st Regio Symposium in Organic and Bioorganic chemistry, 16-20th September 2001, Champery, Switzerland.