Korrekte Voraussage eines sehr guten Outcomes nach Schädel-Hirn-Trauma durch multimodale EP bei klinisch und neuroradiologisch infaust erscheinendem Befund
Multimodal EP Correctly Predicts a Favourable Outcome of Severe Skull-Brain Trauma Following Unpromising Clinical and Neuroradiological FindingsM. Gelzenlichter 1
, E. Maurer 1
, P. Milewski 1
, J. Nothwang 2
1Abteilung für Anästhesie, Klinik am Eichert, Göppingen
2Abteilung für Unfallchirurgie, Klinik am Eichert, Göppingen
Vorgestellt wird der ungewöhnlich positive Verlauf eines schweren Schädel-Hirn-Traumas mit epiduraler Blutung und konsekutiver subtotaler oberer Einklemmung. Trotz infaust erscheinenden klinischen und neuroradiologischen Befunden, zeigten sich in den wiederholt abgeleiteten somatosensorisch evozierten Potenzialen (SEP) immer erhaltene Skalpantworten, und auch in den frühen akustisch evozierten Potenzialen (FAEP) waren stets alle fünf Peaks nachweisbar. Somit konnte eine mögliche Erholung des Zerebrums vorhergesagt werden. Der klinischen Besserung ging eine sukzessive Erholung der anfangs verzögerten kortikalen SEP-Antworten voraus. Multimodal evozierte Potenziale sind in der Lage, trotz klinisch infaust erscheinender Prognose ein gutes Outcome korrekt vorherzusagen. Sie sind bei schweren Verletzungen des ZNS als Standardmonitoring geeignet, zumal es sich um eine wenig aufwändige und schnell erlernbare nichtinvasive Methode handelt.
Abstract
Unusual positive outcome of severe skull-brain trauma with epidural bleeding and consecutive subtotal supratentorial hemiation is presented. Despite unfavourable clinical and neuroradiological findings, repeatedly measured SEPs consistently showed electric scalp potentials. Early acustically evoced potentials also always showed all 5 peaks. This enabled a prediction of positive cerebral outcome. The slow recovery of initial prolonged cortical SEPs preceeded clinical recovery. Multimodal evoked potentials enable us, inspite of, adverse clinical findings, to predict a promising outcome correctly. SEP can be used as easily implemented, quickly learned and non-invasive standard monitoring of severe trauma of the CNS.
Literatur
1
Attia J, Cook D J.
Prognosis in anoxic and trauma coma.
Crit Care Clin.
1998;
14
497-511
2
Barelli A, Valente M R, Clemente A. et al .
Serial multimodality evoked potentials in severely head injured patients: Diagnostic and diagnostic inplications.
Crit Care Med.
1991;
19
1374-1381
3
Brown J I, Moulton R J, Konasiewicz S J, Baker A J.
Cerebral oxydative mechanism and evoked potential deterioriation after severe brain injury: New evidence of early posttraumatic ischemia.
Neurosurgery.
1998;
42
1057-1063
4
Butinar D, Gostinsa A.
Brainstem auditory evoked potentials and somatosensory evoked potentials in prediction of posttraumatic coma in children.
Pflugers Arch.
1996;
431
289-290
5
Carter B G, Taylor A, Butt W.
Severe brain injury in children: long term outcome and its prediction using somatosensory evoked potentials (SSEPs).
Intensive Care Med.
1999;
25
722-728
9
Goodwin S R, Friedman W A, Bellefleur M.
It is time to use evoked potentials to predict outcome in comatose children and adults.
Crit Care Med.
1991;
19
581
10
Guerit J M, Fischer C, Facco E. et al .
Standards of clinical practice of EEG and EPs in comatouse and other unresponsive states. The International Federation of Clinical Neurophysiology.
Electroencephalogr Clin Neurophysiol Suppl.
1999;
52
117-131
11
Hashimoto I, Ishiyama Y, Yoshimoto T, Nemoto S.
Brainstem auditory evoked potentials recorded directly from human brainstem et thalamus.
Brain.
1981;
104
841-859
12
Hutchinson D O, Frith R W, Shaw N A, Judson J A, Cant B R.
A comparison between electroencephalography and somatosensory evoked potentials for outcome prediction following severe head injury.
Electroencephalogr Clin Neurophysiol.
1991;
78
228-233
13
Judson J A, Cant B R, Shaw N A.
Early prediction of outcome from zerebral trauma by somatosensory evoked potentials.
Crit Care Med.
1990;
18
363-368
14
Kiening K L, Unterberg A W, Bardh T F, Schneider G H, Lanksch W R.
Monitoring of zerebral oxygenation in patients with severe head injuries: brain tissue PO2 versus jugular vein oxygen saturation.
J Neurosurg.
1996;
85
751-757
15
Konasiewicz S J, Moulton R J, Shedden P M.
Somatosensory evoked potentials and intracranial pressure in severe head injury.
Can Neurol Sci.
1994;
21
219-226
16
Maurer E, Milewski P.
Anwendungsmöglichkeit und diagnostische Aussagekraft von evozierten Potentialen bei Patienten mit neurologischen Schäden in der operativen Intensivmedizin.
Anästhesiol Intensivmed Notfallmed Schmerzther.
1998;
33
430-440
18
Moulton R J, Brown J I, Konasiewicz S J.
Monitoring severe head injury: a comparision of EEG and somatosensory evoked potentials.
Can J Neurol Sci.
1998;
25
7-11
19
Moulton R J, Shedden P M, Trucker W S, Muller P J.
Somatosensory evoked potential monitoring following severe closed head injury.
Clin Invest Med.
1994;
17
187-195
21
Nitta M, Tsutsui T, Ueda Y. et al .
The effects on an extradural expanding leasion on regional intracranial pressure, blood flow, somatosensory conduction and brain herniation: an experimental study in baboons.
Acta Neurochir.
1990;
104
30-37
22
Pohlmann-Eden B, Dingethal K, Bender H J, Koelfen W.
How reliable is the predictive value of SEP patterns in severe brain damage with special regard to bilateral loss of cortical responses?.
Intensive Care Med.
1997;
23
301-308
23
Riffel B, Stöhr M, Graser W, Trost E, Baumgärtner H.
Frühzeitige Prognose beim schweren Schädel-Hirn-Trauma mittels Glasgow-Coma-Score und evozierter Potentiale.
Anästhesist.
1989;
38
51-59
29
Sleigh J W, Havill J H, Frith R, Kersel D, Marsh N, Ulyatt D.
Somatosensory evoked potentials in severe head injury: a blindet study.
J Neurosurg.
1999;
91
577-580
31
Valdaka A B, Goodman J C, Gopinath S P, Uzura M, Robertson C S.
Comparison of brain tissue oxygen tension to mycrodialysis-based measures of zerebral ischemia in fatally head-injured humans.
Journal of Neurotrauma.
1998;
15
509-519
32
Zeitlhofer J, Steiner M, Zadrobilek E. et al .
Evozierte Potentiale zur Verlaufs- und Prognosebeurteilung von Schädel-Hirn-Trauma-Patienten.
Anästhesist.
1989;
38
10-15