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Z Gastroenterol 2002; 40: 46-56
DOI: 10.1055/s-2002-23612
Osteopathie
© Karl Demeter Verlag im Georg Thieme Verlag Stuttgart · New York

Diagnostik der Osteoporose

Evaluation of OsteoporosisJ. Pfeilschifter1 , P. H. Kann2
  • 1Berufsgenossenschaftliche Kliniken Bergmannsheil, Medizinische Klinik - Uniklinik Bochum
  • 2Klinik und Poliklinik für Innere Medizin, Abteilung für Endokrinologie, Universitätsklinikum Mainz
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Publication History

Publication Date:
04 April 2002 (online)

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Zusammenfassung

Die klinisch-körperliche Untersuchung, die Knochendichtemessung und radiomorphometrische Verfahren sind die Hauptstützen der Osteoporosediagnostik. Eine begrenzte Zahl einfacher Laborparameter reicht meistens aus, um sekundäre Formen einer Osteoporosen und eine Osteomalazie abzugrenzen. Knochenspezifische Umbauparameter spielen eine wachsende Rolle beim Therapiemonitoring. Sie könnten in den kommenden Jahren auch eine Rolle in der Therapieentscheidung spielen. Bei unklaren oder inkonsistenten Befunden ist eine Knochenbiopsie hilfreich. Der Artikel gibt einen aktuellen Überblick über die Möglichkeiten und Grenzen der oben genannten diagnostischen Verfahren.

Abstract

Physical examination, bone densitometry and x-ray are the mainstay in the evaluation of osteoporosis. A limited number of simple blood tests are sufficient to discriminate most secondary forms of osteoporosis and to exclude osteomalacia. Bone-specific biochemical markers play an increasing role in monitoring osteoporosis therapy. They may also play a role in treatment decision in the coming years. Bone biopsies are helpful if findings are unclear or inconsistent. The present review gives a summary of the opportunities and limitations of the above diagnostic procedures.

Schlüsselwörter

Osteoporose - Knochendichtemessung - Osteosonometrie - Knochenbiopsie - Biochemische Marker - Genetische Marker

Key words

Osteoporosis - Bone Densitometry - Osteosonometry - Bone Biopsy - Biochemical Markers - Genetic Markers

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Prof. Dr. J. Pfeilschifter

Berufsgenossenschaftliche Kliniken Bergmannsheil, Medizinische Klinik - Uniklinik Bochum

Bürkle-de-la-Camp-Platz 1

44789 Bochum

Fax: 02 34-3 02 64 03

Email: Johannes.Pfeilschifter@ruhr-uni-bochum.de