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Semin Neurol 2001; 21(4): 407-416
DOI: 10.1055/s-2001-19412
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Pearls and Pitfalls in the Approach to Patients with Neurotoxic Syndromes

Daniel E. Rusyniak
  • Division of Medical Toxicology, Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana
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Publication History

Publication Date:
02 January 2002 (online)

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ABSTRACT

Neurotoxins are an important cause of neurologic disorders. A vast number of potentially neurotoxic compounds exist, including prescription drugs, illicit substances, and exposures through the workplace, residence, hobbies, and the environment. Effects of neurotoxins can mimic neurologic illnesses; therefore, it is important to consider neurotoxins in the differential diagnosis of any patient with neurological dysfunction. Paramount to the diagnosis of a possible neurotoxic syndrome is establishing causation. This can be done by a systematic approach utilizing principles in epidemiology and applying them to the individual patient. This approach is discussed in the following article in an attempt to bring structure to solving problems in a complex area of medicine.

KEYWORD

Neurotoxins - neurotoxicology - clinical approach - epidemiology

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