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Semin Thromb Hemost 2001; 27(6): 639-652
DOI: 10.1055/s-2001-18868
DOI: 10.1055/s-2001-18868
Regulatory Role of Cytokines in Disseminated Intravascular Coagulation
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
06. Dezember 2001 (online)
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ABSTRACT
Disseminated intravascular coagulation (DIC) can complicate a number of diseases. DIC in the setting of sepsis is considered to result from strong activation of the coagulation system and concurrent inhibition of fibrinolysis and other anticoagulant pathways. Cytokines have been implicated as important mediators in these hemostatic alterations. This article summarizes recent insights into which cytokines are likely to be involved in the procoagulant response to systemic infection.
KEYWORD
Cytokines - endotoxin - coagulation - fibrinolysis - protein C
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