RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000083.xml
Synlett 2001; 2001(12): 1889-1892
DOI: 10.1055/s-2001-18770
DOI: 10.1055/s-2001-18770
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
Titanium 3,3′-Modified-Biphenolate Complexes Atropisomerically Controlled by TADDOLs: Novel Chiral Lewis Acid Catalysts for Asymmetric Methylation with an Achiral Methyl-Titanium Reagent
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
04. Dezember 2001 (online)
![](https://www.thieme-connect.de/media/synlett/200112/lookinside/thumbnails/10.1055-s-2001-18770-1.jpg)
Chiral Ti complexes, which are constituted of 3,3′-modified-biphenolate (BIPOLate) ligands atropisomerically controlled by (R)-TADDOLs, are shown to be novel chiral Lewis acid catalysts for the methylation reaction of aldehydes with an achiral methyl-titanium reagent. Thus, the chiral 3,3′-modified BIPOLate/TADDOLate-Ti complexes give enhanced enantioselectivities up to 100% enantiomeric excess.
asymmetric methylation - atropisomer - chiral Lewis acid catalyst - chiral titanium complex - 3,3’-modified biphenols