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Synthesis 2001(15): 2231-2233
DOI: 10.1055/s-2001-18435
DOI: 10.1055/s-2001-18435
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York
Palladium-Catalyzed Cross-Coupling Reaction of Aryltriethoxysilanes with Aryl Bromides under Basic Aqueous Conditions
Further Information
Received
22 August 2001
Publication Date:
05 August 2004 (online)
Publication History
Publication Date:
05 August 2004 (online)
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Abstract
Aryltriethoxysilanes were cross-coupled with aryl bromides in high yield in the presence of a palladium catalyst and aqueous sodium hydroxide.
Key words
siloxane derivatives - cross-coupling - palladium catalyst - aryl bromides - biaryls
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References
Generally, aryltrimethoxysilanes could be prepared from the corresponding arylchlorosilanes. The major product using tetramethyl orthosilicate was diaryl(dimethoxy)silane. See also ref [4b] . Unlike methyl derivatives, ethyl siloxane derivatives are directly prepared by reacting aryl Grignard reagents with tetraethyl orthosilicate in acceptable yields. See Experimental Section.