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Anästhesiol Intensivmed Notfallmed Schmerzther 2001; 36(Suppl 2): 114-116
DOI: 10.1055/s-2001-18179
ARTIFICIAL OXYGEN CARRIERS
© Georg Thieme Verlag Stuttgart · New York

Hemoglobin-Based Oxygen Carriers in der Sepsis

Hemoglobin-based Oxygen Carriers in SepsisH.-G. Bone
  • Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitätsklinikum Münster, Münster
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Publication History

Publication Date:
05 November 2001 (online)

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Schlüsselwörter:

Sepsis - hemoglobin - blood substitute

Literatur

  • 1 Gould S A, Moss G S. Clinical development of human polymerized haemoglobin as a blood substitute.  World J Surgery. 1996;  20 1200-1207
    PubMedSearch in Google Scholar
  • 2 Crowley J P, Metzger J, Gray A, Pivacek L E, Cassidy G, Valeri C R. Infusion of stroma-free cross-linked haemoglobin during acute gram-negative bacteremia.  Circ Shock. 1993;  41 144-149
    PubMedSearch in Google Scholar
  • 3 Bone H G, Schenarts P J, Booke M, McGuire R, Harper D, Traber L D, Traber D L. Pyridoxalated haemoglobin polyoxyethylene conjugate normalizes the hyperdynamic circulation in septic sheep.  Crit Care Med. 1997;  25 1010-1018
    PubMedSearch in Google Scholar
  • 4 Bone H G, Schenarts P J, Fischer S R, McGuire R, Traber L D, Traber D L. Pyridoxalated haemoglobin polyoxyethylene conjugate reverses hyperdynamic circulation in septic sheep.  J Appl Physiol. 1998;  84 1991-1999
    PubMedSearch in Google Scholar
  • 5 Bone H G, Fischer S R, Schenarts P J, McGuire R, Traber L D, Traber D L. Continuous infusion of pyridoxalated haemoglobin polyoxyethylene conjugate in hyperdynamic septic sheep.  Shock. 1998;  10 69-76
    PubMedSearch in Google Scholar
  • 6 Mourelatos M G, Enzer N, Ferguson J L, Rypins E B, Burhop K E, Law W R. The effects of diaspirin cross-linked haemoglobin in sepsis.  Shock. 1996;  5 141-148
    PubMedSearch in Google Scholar
  • 7 Kilbourn R G, DeAngelo J, Bonaventura J. Clinical effects of cell-free haemoglobin, a scavenger of nitric oxide in septic shock. In: Vincent JL (Hrsg) Yearbook of Intensive Care and Emergency Medicine. Springer-Verlag, Berlin u.a. 1997: 230-239
    Search in Google Scholar
  • 8 Griffiths E, Cortes A, Gilbert N, Stevenson P, MacDonald S, Pepper D. Haemoglobin-based blood substitutes and sepsis.  Lancet. 1995;  345 158-160
    CrossrefPubMedSearch in Google Scholar
  • 9 Bone H G, Schenarts P J, Fischer S R, McGuire R, Traber L D, Traber D L. Continuous infusion of pyridoxalated haemoglobin polyoxyethylene conjugate in hyperdynamic septic sheep.  Shock. 1998;  10 69-76
    PubMedSearch in Google Scholar
  • 10 Sielenkämper A, Eichelbrönner O, Martin C M, Madorin, S W, Chin-Yee I H, Sibbald W J. Diaspirin cross-linked haemoglobin improves mucosal perfusion in the ileum of septic rats.  Crit Care Med. 2000;  28 782-787
    PubMedSearch in Google Scholar

Priv.-Doz. Dr. Hans-Georg Bone

Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitätsklinikum Münster

Münster