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Synlett 2001; 2001(8): 1323-1325
DOI: 10.1055/s-2001-16065
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Novel Synthesis of Fully-Substituted Pyridine Derivatives via Self-Condensation of Cyclic Ketones in Aqueous Ammonium Chloride under Hydrothermal Conditions

Hiyoshizo Kotsuki* , Barun K. Mehta, Kazumichi Yanagisawa
  • *Laboratory of Natural Products Synthesis, Faculty of Science, Kochi University, Akebono-cho, Kochi 780-8520, Japan; Fax + 81-88-844-83 59; E-mail: kotsuki@cc.kochi-u.ac.jp
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Publication Date:
31 December 2001 (online)

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A new method for synthesizing fully-substituted pyridine derivatives was developed using the self-condensation of cyclic ketones in aqueous ammonium chloride under hydrothermal conditions.

self-condensation - cyclic ketones - fully-substituted pyridines - aqueous ammonium chloride - hydrothermal reaction