Semin Liver Dis 2001; 21(2): 237-250
DOI: 10.1055/s-2001-15344
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Imaging of Benign Hepatic Masses

Michael P. Federle, Giuseppe Brancatelli
  • Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Further Information

Publication History

Publication Date:
31 December 2001 (online)

ABSTRACT

Using helical CT and rapid IV injection of contrast material, benign hepatic masses are discovered in at least 20% of subjects. To minimize expensive and invasive evaluation, an orderly approach to the interpretation of these lesions is necessary. Many benign lesions have a near pathognomonic appearance on a properly performed and interpreted CT scan. Others can have the diagnosis confirmed by a specific and well-chosen follow-up study, such as contrast-enhanced MR. In this article we present the most common types of benign hepatic masses and our approach to their diagnosis.

REFERENCES

  • 1 Murphy B J, Casillas J, Ros P R. The CT appearance of cystic masses of the liver.  Radiographics . 1989;  9 307-322
  • 2 Ros P R, Taylor H M. Benign tumors of the liver. In: Gore RM, Twine MS, eds. Textbook of Gastrointestinal Radiology Philadelphia: WB Saunders; 2000: 1467-1522
  • 3 Karhunen P J. Benign hepatic tumors and tumor-like conditions in men.  J Clin Pathol . 1986;  39 183-188
  • 4 Freeny P C, Marks W M. Patterns of contrast enhancement of benign and malignant hepatic neoplasms during bolus dynamic and delayed CT.  Radiology . 1986;  160 613-620
  • 5 Quinn S F, Benjamin G C. Hepatic cavernous hemangiomas: simple diagnostic sign with dynamic bolus CT.  Radiology . 1992;  182 545-548
  • 6 Vilgrain V, Boulos L, Vullirme M P. Imaging of atypical hemangiomas of the liver with pathologic condition.  Radiographics . 2000;  20 379-397
  • 7 McFarland E G, Mayo-Smith W W, Sain S. Hepatic hemangiomas and malignant tumors: improved differentiation with heavily T2-weighted conventional spin-echo MR imaging.  Radiology . 1994;  193 43-47
  • 8 Leslie D F, Johnson C M, Ilstrup D M, Harmsen W S. Destruction between cavernous hemangiomas of the liver and hepatic metastases on CT: value of contrast enhancement patterns.  Am J Roentgenol . 1995;  164 625-629
  • 9 Kim T, Federle M P, Baron R L, Peterson M S, Kawanmori Y. Discrimination of small hepatic hemangiomas from small hypervascular malignant tumors with two-phase helical CT.  Radiology (in press).
  • 10 Wanless I R, Albrecht S, Bilbao J. Multiple focal nodular hyperplasia of the liver associated with vascular malformations of various organs and neoplasm of the brain: a new syndrome.  Mod Pathol . 1989;  2 456-462
  • 11 Brancatelli G, Federle M P, Grazioli L. Focal nodular hyperplasia-CT findings in 78 patients with emphasis on multiphasic helical CT.  Radiology . 2001;  219 61-68
  • 12 Nguyen B N, Flejoir J F, Terris B. Focal nodular hyperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms.  Am J Surg Pathol . 1999;  23 1441-1454
  • 13 Mortele K J, Praet M, Van Vlierberghe H. CT and MR imaging findings in focal nodular hyperplasia of the liver: radiologic-pathologic correlation.  Am J Roentgenol . 2000;  175 687-692
  • 14 Carlson S K, Johnson C P, Bender C E, Welch T J. CT of focal nodular hyperplasia of the liver.  Am J Roentgenol . 2000;  174 705-712
  • 15 Vilgrain V, Flejou J F, Arrive L. Focal nodular hyperplasia of the liver: MR imaging and pathologic correlation in 37 patients.  Radiology . 1992;  184 699-703
  • 16 Welch T J, Sheedy P F, Johson C P. Focal nodular hyperplasia and hepatic adenoma: comparison of angiography, CT, US and scintigraphy.  Radiology . 1985;  156 593-595
  • 17 Grazioli L, Morana G, Federle M P. Focal nodular hyperplasia: morphologic and functional MR imaging using gadobenate dimeglumine (Gd-BOPTA).  Radiology (in press).
  • 18 Ichikawa T, Federle M P, Grazioli L. Fibrolamellular hepatocellular carcinoma: imaging and pathologic findings in 31 recent cases.  Radiology . 1999;  213 352-361
  • 19 Grazioli L, Federle M P, Ichikawa T. Liver adenomatosis: clinical, histopathologic, and imaging findings in 15 patients.  Radiology . 2000;  216 395-402
  • 20 Ichikawa T, Federle M P, Grazioli L, Nalesnick M. Hepatocellular adenoma: multiphasic CT and histopathologic findings in 25 patients.  Radiology . 2000;  214 861-868
  • 21 Paulson E K, McClellan J S, Washington K. Hepatic adenoma: MR characteristics and correlation with pathologic findings.  Am J Roentgenol . 1994;  163 113-116
  • 22 Arrive L, Flejon J F, Vilgrain V. Hepatic adenoma: MR findings in 51 pathologically proved lesions.  Radiology . 1994;  193 507-512
  • 23 International Working Party. Terminology of nodular hepatocellular lesions.  Hepatology . 1995;  22 983-993
  • 24 Wanless I R. Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2500 autopsies and a new classification of benign hepatocellular nodules.  Hepatology . 1990;  11 787-796
  • 25 Miller W, Federle M P, Straub W H, Davis P L. Budd-Chiari syndrome: imaging with pathologic correlation.  Abdom Imaging . 1993;  18 329-335
  • 26 Vilgrain V, Lewin M, Vons C. Hepatic nodules in Budd-Chiari syndrome: imaging features.  Radiology . 1999;  210 443-450
  • 27 Roberts J L, Fishman E K, Hartman D S. Lipomatous tumors of the liver: evaluation with CT and US.  Radiology . 1986;  158 613-617
  • 28 Buetow P C, Buck J L, Pantowgrag-Brown L. Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma.  Radiology . 1995;  196 805-810
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