Synlett 2001; 2001(7): 1127-1128
DOI: 10.1055/s-2001-15149
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A New Synthesis of Methyl 3-Oxo-2-pentyl-1-cyclopentene-1-acetate

Khushrav Crawford* , Valentin Rautenstrauch, Arnold Uijttewaal
  • *Firmenich Chemical Manufacturing Center, 150 Firmenich Way, Newark, NJ 07114 USA; Fax + 1 973 344 29 99; E-mail: khushrav.crawford@firmenich.com
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2001 (online)

The 92 : 8 equilibrium mixture of (±)-trans-methyl dihydrojasmonate (1) and its cis-isomer is transformed in 63% overall yield into the title compound 4 by epoxidation of the derived enol acetate 2 with peracetic acid/Na2CO3 in toluene and heating the resulting α-acetoxy epoxide 3 in MeOH in the presence of catalytic amounts of methanesulfonic acid.