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DOI: 10.1055/s-2001-14286
Pneumonectomy for Lung Cancer in Heart Transplant Recipient
Publication History
Publication Date:
31 December 2001 (online)
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Prolonged nonspecific immunosuppression after solid-organ transplantation is associated with an increased risk of certain cancers [1]. Review of the medical literature reveals that the combination of profound immunossuppression (triple-drug immunosuppression), a heavy smoking history, advanced age and a working exposition puts cardiac transplant recipients at increased risk for the development of aggressive Iung cancer [2]. These tumors in cardiac transplant recipients carry a poor prognosis. We present one case of bronchogenic carcinoma in a cardiac transplant patient. The patient was operated to resect the tumor and a long-term cure and a good quality of life should, however, be offered.
Key words:
Cardiac Transplant - Lung Cancer - Pneumonectomy
References
- 1 Pham S M. et al . Solid Tumors after Heart Transplantation: Lethality for Lung Cancer. Ann Thorac Surg. 1995; 60 1623-1626
- 2 Johanson W M. et al . Double Jeopardy: Lung Cancer After Cardiac Transplantation. Chest. 1998; 113 1720-1723
- 3 Penn I. Incidence and treatment of neoplasia after transplantation. J Heart Lung Transplant. 1993; 12 328-336
- 4 Flemming R H, Jennison S H, Naunheim K S. Primary Bronchogenic Carcinoma in the Heart Transplant Recipient. Ann Thorac Surg. 1994; 57 1300-1301
Received for Publication: July 13, 2000
Justus Thomas Strauch
Department of Cardiovascular Surgery
Friedrich-Schiller-University Jena
Bachstraße 18
07743 Jena
Germany
Phone: +49-3641-934805
Fax: +49-3641-934802
Email: justus.strauch@med.uni-jena.de