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Synlett 2001; 2001(2): 0266-0268
DOI: 10.1055/s-2001-10762
DOI: 10.1055/s-2001-10762
letter
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Cedranediolborane as a Borylating Agent for the Preparation of Boronic Acids: Synthesis of a Boronated Nucleoside Analogue
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Publikationsverlauf
Publikationsdatum:
31. Dezember 2001 (online)
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Cedranediolborane can be cross-coupled with aryl iodides under Pd(0) catalysis to yield aryl boronates which can easily be deprotected to form the corresponding free boronic acids. The application of this methodology has led to the preparation of a boronated nucleoside indole analogue.
cedrane - borylation - boronic acids - boronates - nucleoside