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Am J Perinatol 2000; 17(3): 151-158
DOI: 10.1055/s-2000-9975
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

SEVERE AORTIC THROMBOSIS IN THE NEONATE-SUCCESSFUL TREATMENT WITH LOW-MOLECULAR-WEIGHT HEPARIN: TWO CASE REPORTS AND REVIEW OF THE LITERATURE

Gil Klinger1,3 , Jonathan Hellmann1,3 , Alan Daneman23
  • 1Division of Neonatology, Department of Pediatrics, The Hospital for Sick Children, Toronto and the
  • 2Department of Radiology, The Hospital for Sick Children, Toronto
  • 3The University of Toronto, Toronto, Ontario, Canada
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Publication History

Publication Date:
19 August 2004 (online)

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ABSTRACT

Small- to moderate-sized aortic thrombi in the sick newborn are frequently demonstrated, however, severe aortic thrombosis is rarely encountered. We report two newborn infants presenting with signs of decreased lower limb perfusion shortly after birth. An occlusive infrarenal aortic thrombus was demonstrated in both infants by ultrasound. No predisposing condition for thrombosis could be found in the first infant; in the second, an umbilical arterial catheter was the likely cause. The infants were successfully treated with low-molecular-weight heparin. In both infants resolution of the thrombus was observed by ultrasound. No complications of treatment were encountered. The clinical spectrum of neonatal aortic thrombosis and treatment options are reviewed.

KEYWORD

Aortic thrombosis - neonate - low-molecular-weight heparin - treatment complications - review

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