Planta Med 2000; 66(6): 560-563
DOI: 10.1055/s-2000-8652
Letter
Georg Thieme Verlag Stuttgart · New York

Chemical Analysis and Antimicrobial Studies on Three Species of Ferulago from Greece

Costas Demetzos1,*, Dimitrios Perdetzoglou1 , Maria Gazouli2 , Kit Tan3 , Costas Economakis4
  • 1 School of Pharmacy, Department of Pharmacognosy, Panepistimiopolis, University of Athens, Athens, Greece
  • 2 Department of Bacteriology, Hellenic Pasteur Institute, Athens, Greece
  • 3 Botanical Institute, University of Copenhagen, Copenhagen K, Denmark
  • 4 Institute of Olive Trees and Subtropical Plants, Chania, Crete, Greece
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Abstract

The chemical composition of the essential oils of the flowering parts and of the hexane extracts of the leaves, of three species of the genus Ferulago (Apiaceae) from Greece, i.e., F. thyrsiflora, F. sylvatica and F. nodosa, was analysed by GC and GC-MS. Manoyl oxide isomers and lupanine, were identified in the hexane extracts of F. thyrsiflora. Dillapiole, was identified in all hexane extracts. Ent-3β-hydroxy-13-epi-manoyl oxide was identified and isolated from the essential oil of F. thyrsiflora. All these compounds are new reports for the genus Ferulago and are useful chemotaxonomic markers. Chemical data of F. thyrsiflora is presented for the first time. The essential oils and the extracts were investigated for their antimicrobial activity against Gram-positive and Gram-negative microorganisms.

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Prof. Dr. Ass. Costas Demetzos

School of Pharmacy Department of Pharmacognosy

Panepistimiopolis Zografou 15771

Athens

Greece

Email: demetzos@galenos.pharm.uoa.gr

Phone: +30-1-7274596