Download PDF
Synlett 2000; 2000(11): 1643-1645
DOI: 10.1055/s-2000-7951
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Michael Reactions in Water Using Amphiphilic Resin-Supported Quaternary Ammonium Hydroxides

Kazutaka Shibatomi* , Toshiyuki Nakahashi, Yasuhiro Uozumi
  • *Institute for Molecular Sciences, Myodaiji, Okazaki 444-8585, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Quaternary ammonium hydroxides were immobilized on a polystyrene-poly(ethylene glycol) copolymer resin. The amphiphilic polymer-supported ammonium hydroxides catalyzed Michael reaction of cyclic β-keto esters with several Michael acceptors in water to give corresponding adducts in high yields.

polymer-supported ammonium salts - phase-transfer catalysis - Michael additions - aqueous medium - solid-phase synthesis

      >