Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 2000; 2000(10): 1470-1472
DOI: 10.1055/s-2000-7628
DOI: 10.1055/s-2000-7628
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
Highly Regio- and Enantioselective Heck Reactions of N-Substituted 2-Pyrroline with the New Chiral Ligand BITIANP
Further Information
Publication History
Publication Date:
31 December 2000 (online)
![](https://www.thieme-connect.de/media/synlett/200010/lookinside/thumbnails/10.1055-s-2000-7628-1.jpg)
The intermolecular Heck reaction of N-substituted 2-pyrroline 4 with aryl triflates 5a-d in the presence of the chiral ligand (S)-BITIANP 1 gives the N-substituted 5-aryl-2-pyrrolines 6a-d highly regioselectively with excellent enantioselectivity (93-95% ee) and good yields (80-92%). In addition, cyclohexenyl triflate 8 can be transformed with 91% ee.
alkaloids - asymmetric catalysis - chiral ligands - enantioselective Heck reaction - palladium