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DOI: 10.1055/s-2000-6910
© Georg Thieme Verlag Stuttgart · New York
M. Castleman - seltene Differenzialdiagnose eines retroperitonealen Tumors
Publication History
Publication Date:
31 December 2000 (online)
![](https://www.thieme-connect.de/media/viszeralchirurgie/200004/lookinside/thumbnails/10.1055-s-2000-6910-1.jpg)
Zusammenfassung.
Beim M. Castleman handelt es sich um eine seltene lymphoproliferative Erkrankung im Sinne eines Prälymphoms. Ätiologisch und pathogenetisch kommen einer Infektion mit dem humanen Herpes Virus 8 sowie einem Anstieg des Immunmodulators Interleukin 6 eine gewisse Rolle zu. Überlappungssyndrome mit verschiedenen Autoimmunerkrankungen werden beschrieben. Therapeutische Ansätze stellen die Operation und verschiedene Chemotherapie-Schemata dar. In unserer Klinik exstirpierten wir bei einem 61-jährigen Patienten einen linksseitigen retroperitonealen Tumor, der sich als zirkumskripter M. Castleman herausstellte. Eingriff und postoperativer Verlauf waren unauffällig; eine weitere adjuvante Therapie war nicht erforderlich.
M. Castleman - rare differential diagnosis of a retroperitoneal tumor.
Castleman's disease is a lymphoproliferative disorder nowadays understood as a prelymphoma. Infection with human herpes virus 8 and an increase of interleukin 6 seem to play an important role in etiology and pathogenesis. Associations with several autoimmune diseases do exist and therapy consists of surgery and chemotherapy. In our hospital we excided a tumor from the left retroperitoneum in a 61 year old patient. Histologically it was a localized Castleman's disease. Surgery and hospital stay were without any complication and there was no indication for further adjuvant therapy.
Schlüsselwörter:
M. Castleman - lymphoproliferative Erkrankung - zwei Subtypen - HHV 8 - AIDS
Key words:
M. Castleman - lymphoproliferative disorder - 2 types - HHV 8 - AIDS
Literatur
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Dr. med. A. Schaper
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Zentrum Pharmakologie und Toxikologie
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