RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000083.xml
Synlett 2000; 2000(7): 0955-0958
DOI: 10.1055/s-2000-6661
DOI: 10.1055/s-2000-6661
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
Easy Synthesis of New 2-Oxo-2,3-dihydro-1H-pyrrolo[1,2-b]pyrazole Systems
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
![](https://www.thieme-connect.de/media/synlett/200007/lookinside/thumbnails/10.1055-s-2000-6661-1.jpg)
1,2-Diaza-1,3-butadienes react with dialkyl 1,3-acetonedicarboxylate in the presence of potassium carbonate to give 2-hydroxy-2,3-dihydro-1H-1-aminopyrroles that in turn produce 1-aminopyrroles by dehydration in the presence of copper(II)trifluoromethansulfonate. The treatment of these compounds with sodium hydride leads to NH-substituted 2-oxo-2,3-dihydro-1H-pyrrolo[1,2-b]pyrazole. Under the same reaction conditions, NH-BOC protected 1-aminopyrroles, after acidic cleavage of the BOC protecting group, afford NH-unsubstituted 2-oxo-2,3-dihydro-1H-pyrrolo[1,2-b]pyrazole.
1,2-diaza-1,3-butadienes - Michael additions - cyclization - pyrrolo[1,2-b]pyrazoles