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Synlett 2000; 2000(7): 0993-0994
DOI: 10.1055/s-2000-6660
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Microwave Thermolysis VII: Selective Diversity In The Reduction Using Sodium Hypophosphite Under Microwave Irradiation

H. M. Meshram* , Y. S. S. Ganesh, K. Chandra Sekhar, J. S. Yadav
  • *Indian Institute of Chemical Technology, Hyderabad, India-500 007; Fax + 91 40 7170512; E-mail: yadav@iict.ap.nic.in
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Publication Date:
31 December 2000 (online)

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The selective reduction of nitro group into amine using sodium hypophosphite under microwave irradiation is described. The rapid reaction, solvent free conditions and selectivity over common functional groups like CN, OH, COOH, CONH2 and halogens are the distinct features of the procedure.

catalytic transfer hydrogenation - selective reduction