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Synthesis 2000; 2000(5): 643-645
DOI: 10.1055/s-2000-6395
DOI: 10.1055/s-2000-6395
short paper
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Synthesis of New 4-Cyclohexylcoumarin Derivatives
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Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
![](https://www.thieme-connect.de/media/synthesis/200005/lookinside/thumbnails/10.1055-s-2000-6395-1.jpg)
4-Cyclohexyl-7-hydroxycoumarin (3) and 4-cyclohexyl-6-hydroxycoumarin (8) have been synthesized and used as key intermediates to prepare the potential antipsychotics 10 and 11 by coupling with a piperazine derivative.
4-cyclohexylcoumarins - arylpiperazines - Wittig reaction - Reformatsky reaction - cyclization - heterocycles