Download PDF
Synlett 1999; 1999(S1): 860-862
DOI: 10.1055/s-1999-3083
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Construction of the 6-Azabicyclo[3.2.1]octane Ring System via Higher-Order Cycloaddition; Formal Total Synthesis of (±)-Peduncularine

James H. Rigby* , J. Hoyt Meyer
  • *Department of Chemistry, Wayne State University, Detroit, MI 48202-3489, USA; Fax +1(3 13)5 77 13 77; E-mail: jhr@chem.wayne.edu
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

The azabicyclo[3.2.1]octane core of the Aristotelia alkaloid, peduncularine has been prepared employing a chromium(0)-promoted [6π + 2π] isocyanate/triene cycloaddition reaction as the key ring-forming step.

peduncularine - higher-order cycloaddition - chromium(0)-promoted - azabicyclo[3.2.1]octane - [6π + 2π]cycloaddition