Synlett 1999; 1999(12): 1927-1929
DOI: 10.1055/s-1999-2991
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Distannoxane-Catalyzed Selective Acetylation of 3-Chloropropane-1,2-diol: A Convenient Synthesis of Enantiopure Epichlorohydrin

Akihiro Orita* , Toshihide Ito, Yutaka Yasui, Junzo Otera
  • *Department of Applied Chemistry, Okayama University of Science, Ridai-cho, Okayama 700-0005, Japan
Further Information

Publication History

Publication Date:
31 December 1999 (online)

A distannoxane catalyst effects exclusive acetylation of the primary alcohol of 3-chloropropane-1,2-diol. This reaction provides a convenient access to enantiopure epichlorohydrin.