Synlett 1999; 1999(10): 1636-1638
DOI: 10.1055/s-1999-2918
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Highly Efficient Conversion of Benzoates to Alcohols with Sodium Borohydride in DME-MeOH

Atsuhiko Zanka* , Hiroki Ohmori, Takumi Okamoto
  • *Technological Development Laboratories, Fujisawa Pharmaceutical Co. Ltd., 2-1-6 Kashima, Yodogawa-ku, Osaka, 532-8514, Japan; Fax +81 6 63 90 11 83; E-mail: atsuhiko_zanka@po-fujisawa.co.jp
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 1999 (online)

Methoxybenzoates were quantitatively reduced to the corresponding alcohols with sodium borohydride in a mixed solvent (DME-MeOH). The described method was applicable to a large scale synthesis.