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Synlett 1999; 1999(10): 1615-1617
DOI: 10.1055/s-1999-2906
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Asymmetric Transfer Hydrogenation of α-Amino and α-Alkoxy Substituted Ketones

Jennifer A. Kenny* , Matthew J. Palmer, Athene R. C. Smith, Tim Walsgrove, Martin Wills
  • *Department of Chemistry, Warwick University, Coventry, CV4 7AL, UK; Fax + 24 76 52 41 12; E-mail: m.wills@warwick.ac.uk
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Publication Date:
31 December 1999 (online)

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Through the use of appropriate protecting groups, the asymmetric transfer hydrogenation of ketones bearing heteroatoms at the α-position may be achieved in high yield and enantioselectivity.

enantioselective - catalysis - aminoalcohol - transfer - hydrogenation