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Synlett 1999; 1999(4): 468-470
DOI: 10.1055/s-1999-2636
DOI: 10.1055/s-1999-2636
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
Domino-Reaction of Oxal(imidoyl)chlorides with 3-Aminoisoxazoles: Regio- and Stereoselective Synthesis of 1,4-Dihydro-imidazo[4,5-b]quinoxalines
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Publikationsverlauf
Publikationsdatum:
31. Dezember 1999 (online)
![](https://www.thieme-connect.de/media/synlett/199904/lookinside/thumbnails/10.1055-s-1999-2636-1.jpg)
The reaction of pyrazole and triazole-derived dinucleophiles with oxalic acid-bis(imidoyl)chlorides afforded the novel pyrazo[2,1-b]imidazolidines and imidazo[2,1-c]triazoles, respectively. The use of 3-aminoisoxazoles resulted in a domino reaction leading to biologically relevant 1,4-dihydro-imidazo[4,5-b]quinoxalines
domino-reactions - oxalic acid dielectrophiles - ambident nucleophiles - N-heterocycles - regioselective cyclizations