Download PDF
Synlett 1999; 1999(3): 317-318
DOI: 10.1055/s-1999-2616
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Facile Regio- and Stereocontrolled Synthesis of (E)-Disubstituted Vinyl Sulfones via Transformation of Alkenylzirconocenes with Sulfonyl Chlorides

De-Hui Duan* , Xian Huang
  • *Department of Chemistry, Zhejiang University (Campus Xixi), Hangzhou, Zhejiang, P.R. China, 310028; Fax 86 5 71 8 80 70 77; E-mail: huangx@public.hz.zj.cn
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

Alkenylzirconium reagents, readily obtained by hydrozirconation of terminal alkynes, can smoothly react with sulfonyl chlorides to afford (E)-disubstituted vinyl sulfones in moderate to good yields. Some γ-functionalized vinyl sulfones can be also conveniently synthesized.

vinyl sulfone - hydrozirconation - alkenylzirconocene - sulfonyl chloride - γ-functionalized vinyl sulfone