Download PDF
Synlett 1999; 1999(2): 249-266
DOI: 10.1055/s-1999-2586
new tools in synthesis
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Fourier Transform-Ion Cyclotron Resonance-Mass Spectrometer as a New Tool for Organic Chemists

Jan St. Pyrek*
  • *University of Kentucky Mass Spectrometry Facility, ASTeCC Bldg, Lexington, KY 40506-0286, USA; E-mail: jpyrek1@pop.uky.edu
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download Permissions and Reprints All articles of this category

Currently, mass spectral determination of molecular weights and elemental compositions of synthetic products is a common practice. It is aided by truly impressive developments in methods and instrumentation enabling to characterize great variety of compounds including even those of a relatively high molecular weight. Confidence in such measurements, however, depends upon selecting a suitable ionization method, unambiguous identification of a molecular-type ion, and the adequate precision of mass determinations. This review addresses major aspects of the ion formation and analysis with special attention given to the ion-cyclotron resonance. This powerful technique, different in its principle from most other methods of ion analysis, offers a superb combination of ion manipulation and measurement parameters and full compatibility with an array of ionization methods.

mass spectrometry - ultra-high resolution mass spectrometry - ion-cyclotron-resonance - soft ionization - stable isotopes - molecular weight determination

      >