Three New Tazettine-Type Alkaloids from Galanthus gracilis and Galanthus plicatus Subsp.  byzantinus

Nehir Ünver; Seda Noyan; Tekant Gözler; Mustafa Ali Önür; Belkıs Gözler; Manfred Hesse

doi:10.1055/s-1999-14062

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Planta Med 1999; 65(4): 347-350
DOI: 10.1055/s-1999-14062

Original Paper

Georg Thieme Verlag Stuttgart · New York

Three New Tazettine-Type Alkaloids from Galanthus gracilis and Galanthus plicatus Subsp. byzantinus

Nehir Ünver¹ , Seda Noyan¹ , Tekant Gözler¹ , Mustafa Ali Önür¹ , Belkıs Gözler¹ , Manfred Hesse²

¹Faculty of Pharmacy, Ege University, İzmir, Turkey
²Institute of Organic Chemistry, University of Zürich, Zürich, Switzerland

Further Information

Publication History

September 4, 1998

December 5, 1998

Publication Date:
31 December 1999 (online)

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Abstract:

Three new tazettine-type alkaloids were isolated from two different Galanthus species of Turkish origin. (+)-Isotazettinol and (+)-3-O-demethylmacronine are obtained from G. gracilis, while (+)-3- O-demethyl-3-epimacronine is found in G. plicatus subsp. byzantinus. The known base, trispheridine, is reported for the first time in Galanthus genus.

Key words:

Galanthus gracilis - G. plicatus subsp. byzantinus - Amaryllidaceae - tazettine-type alkaloids - trispheridine