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Synlett 1998; 1998(12): 1337-1338
DOI: 10.1055/s-1998-1954
DOI: 10.1055/s-1998-1954
letter
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Synthesis of (±)-4-Substituted Pipecolinic Acids from 4-Alkylpyridines
Further Information
Publication History
Publication Date:
31 December 2000 (online)
Starting from various 4-alkylpyridines, the phenyldimethylsilyl group was introduced using their 1-acylpyridium salts and its oxidative unmasking afforded the corresponding pipecolinic acids.
pipecolinic acid - oxidative unmasking of silicon - 4-alkyl-pyridines - Sharpless oxidation