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Synlett 1998; 1998(12): 1390-1392
DOI: 10.1055/s-1998-1943
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Synthesis of Spiro Ethers by Ring Closing Metathesis

Martin E. Maier* , Michael Bugl
  • *Institut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Germany; Fax (+ 49) 7071 29 5137; E-mail: martin.e.maier@uni-tuebingen.de
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Publication History

Publication Date:
31 December 2000 (online)

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Starting from the cyclic ketones 1 a - d, the dienes 3 a - e were prepared. The ring closing metathesis reaction of these dienes using the Grubbs catalyst 5 provided the corresponding spiro ethers 4 a - e in good yield. Force field calculations indicate that the conformer with the oxygen in axial position is favored.

ring closing metathesis - spiro compounds