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Synlett 1998; 1998(5): 531-533
DOI: 10.1055/s-1998-1703
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Use of the Ireland-Claisen Rearrangement in the Synthesis of 2,3-Disubstituted Succinates

Lisa M. Pratt* , Stephen A. Bowles, Sally F. Courtney, Christopher Hidden, Christopher N. Lewis, Fionna M. Martin, Richard S. Todd
  • *British Biotech Pharmaceuticals Limited, Watlington Road, Cowley, Oxford, OX4 5LY, UK; Fax 0 18 65 78 08 14; E-mail: martinf@britbio.co.uk
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Publication History

Publication Date:
31 December 2000 (online)

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The Ireland-Claisen rearrangement was employed in a convenient one-pot stereoselective procedure for the synthesis of 2,3-disubstituted succinates (1).

Ireland-Claisen rearrangement - stereoselective - chiral succinates