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Synlett 1998; 1998(4): 385-386
DOI: 10.1055/s-1998-1669
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A New Route to Nitrile Oxides from Primary Alkylhalides for in situ Dipolar Cycloadditions

Dilipkumar Maiti* , Pranab K. Bhattacharya
  • *Medicinal Chemistry Division, Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Calcutta 700 032, India; Fax 91-33-4 73 02 84/4 73 51 97; E-mail: IICHBIO@GIASCIL01.VSNL.NET.IN
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Publication Date:
31 December 2000 (online)

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A new route to nitrile oxide preparation from primary alkylbromide, chloride, nitrite and their cycloadditions with olefins to form isoxazolines in a single pot are described.

nitrilde oxide - in situ - dipolar - cycloaddition - isoxazoline