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Synlett 1998; 1998(3): 316-318
DOI: 10.1055/s-1998-1631
DOI: 10.1055/s-1998-1631
letter
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Synthesis of Calystegine B2 Analogs by Tandem Tautomerization-Intramolecular Glycosylation of Thioureidosugars
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Publication History
Publication Date:
31 December 2000 (online)
![](https://www.thieme-connect.de/media/synlett/199803/lookinside/thumbnails/10.1055-s-1998-1631-1.jpg)
Ring-modified analogs of calystegine B2, a powerful glycosidase inhibitor of the polyhydroxy-nor-tropane series, have been prepared in one-pot reaction from thiourea-carbohydrate precursors via a tandem tautomerization-intramolecular glycosylation process.
calystegine - thiourea - glycosidase inhibitors - azasugar - iminosugar