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Synlett 1997; 1997(11): 1249-1250
DOI: 10.1055/s-1997-5793
DOI: 10.1055/s-1997-5793
letter
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A Thermal Bicyclization: Synthesis of Substituted 2,3,5,6-Tetrahydro-6-oxo-1H-pyrrolizines
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Publication History
Publication Date:
31 December 2000 (online)
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2,3,5,6-Tetrahydro-6-oxo-1H-pyrrolizines, which are potential precursors of 2,3-dihydro-1H-pyrrolizines, were synthesized by a smooth thermal acid-promoted bicyclization of ω-acetylenic aminoesters.
thermal bicyclization - ω-acetylenic aminoester - 2,3,5,6-tetrahydro-6-oxo-1H-pyrrolizine - 2,3-dihydro-1H-pyrrolizine