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Synlett 1997; 1997(8): 905-906
DOI: 10.1055/s-1997-5789
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Synthesis of (-)-Pseudoconhydrine through Ring Enlargement of a L-Proline Derivative

Janine Cossy1 , Cécile Dumas, Domingo Gomez Pardo2
  • 1Laboratoire de Chimie Organique, Associé au CNRS, ESPCI, 10 rue Vauquelin - 75231 Paris Cedex 05, France, Fax: 33.1.40.79.44.25; E-mail: janine.cossy@espci.fr
  • 2Laboratoire de Chimie Organique, Associé au CNRS, ESPCI, 10 rue Vauquelin - 75231 Paris Cedex 05, France, Fax: 33.1.40.79.44.25
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Publication History

Publication Date:
31 December 2000 (online)

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A short synthesis of (-)-pseudoconhydrine is described from L-proline by using a ring enlargement reaction.

L-proline - piperidin-3-ol - enantiospecific ring enlargement - (-)-pseudoconhydrine