Synlett 1997; 1997(7): 801-802
DOI: 10.1055/s-1997-5779
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Conversion of Alkyl Halides into Alcohols Using a Near Stoichiometric Amount of Molecular Oxygen: An Efficient Route to 18O- and 17O-Labeled Alcohols

Masaya Sawamura, Yasuhide Kawaguchi, Eiichi Nakamura*
  • *Department of Chemistry, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

In the presence of near stoichiometric amount of molecular oxygen, various alkyl halides were converted to the corresponding alcohols in high yields through aerobic radical reaction promoted by a Bu2(t-Bu)SnCl/NaBH3CN catalytic system. Isotope-labeled alcohols were prepared with 18O2 and 17O2 without loss of the isotopic purities of the starting oxygen gases.