Download PDF
Synlett 1997; 1997(6): 669-670
DOI: 10.1055/s-1997-3264
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Highly Stereoselective Introduction of Fluorine-Containing Methyl Groups at 2 Position of D-Glucose

Shuichi Hiraoka, Takashi Yamazaki* , Tomoya Kitazume
  • *Department of Bioengineering, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama 226, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Highly stereoselective introduction of fluorine-containing methyl groups at the 2 position of methyl glucoside was attained by use of the difluoromethylene derivative as a key intermediate via hydrogenation of exo- and endo-olefins, whose diastereofacial selectivity was considered to be governed by the anomeric methoxy group.

fluorine-containing methyl groups - difluoromethylene carbohydrate

      >