PDF herunterladen
Synlett 1997; 1997(6): 691-692
DOI: 10.1055/s-1997-3246
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Enantioselective Synthesis of γ-Hydroxynorvaline

M. Jacob, M. L. Roumestant* , P. Viallefont, J. Martinez
  • *Laboratoire des Aminoacides, Peptides et Proteines, ESA CNRS 5075, Université Montpellier I & II, 2, Place E. Bataillon, 34095 Montpellier Cedex 05, France, Fax (33) 04 67144866; roumestant@crit.univ-montp2.fr
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2000 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

A new synthesis of enantiomerically pure γ-hydroxynorvaline is described. The key step involves diastereoselective alkylation of the chiral Schiff base 1 with primary iodo derivatives 2 easily prepared from propylene oxide.

γ-hydroxynorvaline - alkylation - 2-hydroxypinan-3-one - epoxide