Download PDF
Synlett 1997; 1997(5): 580-582
DOI: 10.1055/s-1997-3236
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Total Synthesis of (-)-Balanol

Hideto Miyabe, Mayumi Torieda, Toshiko Kiguchi, Takeaki Naito*
  • *Kobe Pharmaceutical University, Motoyamakita, Higashinada, Kobe 658, Japan, Fax 078 441 7556, E-mail: taknaito@kobepharma-u.ac.jp
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

The total synthesis of (-)-balanol, a potent protein kinase C inhibitor, is described. The synthesis includes a radical cyclization approach to the hexahydroazepine-containing fragment and a biomimetic route to the benzophenone fragment.

(-)-balanol - total synthesis - radical cyclization - oxime ether - chrysophanic acid

      >