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Synthesis 1997; 1997(5): 541-544
DOI: 10.1055/s-1997-1235
DOI: 10.1055/s-1997-1235
paper
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A Convenient Enzymatic Route to Optically Active 1-Aminoindan-2-ol: Versatile Ligands for HIV-1 Protease Inhibitors and Asymmetric Syntheses
Further Information
Publication History
Publication Date:
31 December 2000 (online)
(1S,2R)- and (1R,2S)-1-aminoindan-2-ol were prepared in high enantiomeric excess (>96%) by an immobilized lipase-catalyzed selective acylation of racemic trans-1-azidoindan-2-ol.
enzymatic - resolution - 1-aminoindan-2-ol