Download PDF
Synlett 1997; 1997(12): 1400-1402
DOI: 10.1055/s-1997-1041
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Convenient Synthesis of Nitrogen-Containing Heterocycles Bearing Amino Substituents from Heteroaryl Triflates

Sandro Cacchi* , Antonella Carangio, Giancarlo Fabrizi, Leonardo Moro, Paola Pace
  • *Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università “La Sapienza”, P.le A. Moro 5, 00185 Roma, Italy, Fax: +39 (6) 4991.2780; e-mail: cacchi@axrma.uniroma1.it
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Nitrogen-containing heterocycles bearing amino substituents were prepared by the reaction of the corresponding nitrogen-containing heteroaryl triflates with amines. The reaction affords good results with primary and secondary amines, and with aliphatic and aromatic amines. The whole triflation/amination process can also be conducted as a one-pot operation.

heteroaryl triflates - substitution - heterocycles - quinolines - pyridines

      >