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Synlett 1996; 1996(11): 1041-1042
DOI: 10.1055/s-1996-5669
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Synthesis of Enantiopure Vitamin E via Sharpless Bishydroxylation of an Enyne

Lutz F. Tietze* , Jochen Görlitzer
  • *Institut für Organische Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, D-37077 Göttingen, Germany, Fax +49(551)399476
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Publication Date:
31 December 2000 (online)

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A formal synthesis of enantiopure vitamin E via Sharpless bishydroxylation of the enyne 7a to give the diol 9a as the key step is described.

vitamin E - enyne - bishydroxylation - palladium - alkynes - coupling

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