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Synlett 1996; 1996(6): 507-508
DOI: 10.1055/s-1996-5476
DOI: 10.1055/s-1996-5476
letter
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A Simple One-Pot Preparation of N,N’-Unsymmetrical Ureas from N-Boc Protected Primary Anilines and Amines
Further Information
Publication History
Publication Date:
31 December 2000 (online)
N-Boc protected primary amines and anilines can be converted efficiently into N,N’-unsymmetrically substituted ureas by sequential deprotonation and condensation with amines at 65°C.
amine - aniline - carbamate - unsymmetrical urea